• Febuxosat (Uloric)

    What is febuxostat (Uloric)?

    Febuxostat reduces the production of uric acid in your body. Uric acid buildup can lead to gout or kidney stones. Febuxostat is used to treat gout. ULORIC is not recommended for the treatment of asymptomatic hyperuricemia (high uric acid in the blood).


    How do I take Uloric?

    One 40 mg or 80 mg pill daily is the usual dosing. You can take ULORIC with or without food. You can take ULORIC with antacids. You can take ULORIC without changing your dose if you are taking certain common medications, including: Colchicine, Naproxen, Indomethacin, and Warfarin.


    What should I discuss with my doctor before taking febuxostat (Uloric)?

    You should not use this medication if you are allergic to febuxostat, or if you are being treated with any of the following medications:

    Azathioprine (Imuran);

    Mercaptopurine (Purinethol); or

    Theophylline (Uniphyl).

    If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before taking febuxostat, tell your doctor if you have: kidney disease; liver disease; heart disease, high blood pressure; or diabetes.



    What are the possible side effects of febuxostat (Uloric)?

    Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.


    Stop using febuxostat and call your doctor at once if you have any of these serious side effects:

    • chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
    • Sudden numbness or weakness, especially on one side of the body;
    • Sudden headache, confusion, problems with vision, speech, or balance;
    • Pale skin, easy bruising or bleeding;
    • Nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice;
    • Blood in your urine; or
    • Urinating less than usual.


    What happens if I miss a dose (Uloric)?

    Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose

    What safety information I should know about Uloric?

    • Some patients may experience a gout flare-up when they start taking Uloric. Your doctor may prescribe a NSAID or colchicine to take to help control or prevent a gout flare-up.
    • Do not stop taking this medication if you experience a gout flare-up without talking to your doctor.
    • Lab tests, including uric acid levels and kidney, liver, and heart function, may be performed while you use Uloric.
    • Use Uloric with caution in the elderly; they may be more sensitive to its effects.
    • Uloric should be used with extreme caution in children younger than 18 years old; safety and effectiveness in these children have not been confirmed.

    What about pregnancy and breastfeeding?

    If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Uloric while you are pregnant. It is not known if Uloric is found in breast milk. If you are or will be breast-feeding while you use Uloric, check with your doctor. Discuss any possible risks to your baby.


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