• XOLAIR: Patient Information


    Who is XOLAIR for?

    XOLAIR*(omalizumab) is a prescription medicine that has been shown to significantly decrease the incidence of asthma attacks and improve control of asthma symptoms in people who:

    • Are 12 years of age or older

    • Have moderate to severe persistent asthma

    This means they have 1or more of the following:

    –       Asthma symptoms everyday

    –       Daily need for a rescue inhaler

    –       2 or more asthma attacks a week

    –       1 or more nights a week waking up with asthma symptoms

    –       Continue to have symptoms even though they are taking inhaled steroids on a regular basis, which are also known as “controllers”


    What is IgE?

    IgE is the abbreviation for immunoglobulin E. This substance, which occurs naturally in your body in small amounts, plays an important role in allergic asthma. If you have allergic asthma, your body makes more IgE when you breathe in an allergen that triggers your asthma. This can cause a series of chemical reactions in a process known as the “allergic-inflammatory cascade in allergic asthma”.


    What are the differences between XOLAIR and your other asthma medications?

    XOLAIR* is an IgE blocker, meaning it blocks a substance called IgE. XOLAIR* is used for treating moderate to severe allergic asthma.XOLAIR* works by helping asthma medications work in this process to block IgE from causing the reactionsthat can lead to asthma attacks and symptoms before they start.


    What are the possible side effects of XOLAIR?

    The most common side effects reported in patients who received XOLAIR:

    • Injection site reaction (bruising, redness, warmth, burning, stinging)

    • Viral infections

    • Upper respiratory tract infections

    • Sinusitis

    • Headache

    • Sore throat

    Other less commonly observed side effects included pain, broken bones, leg pain, dizziness, joint pain, muscle pain, joint swelling, and hair loss.


    Who should not receive XOLAIR?

    You should not be given XOLAIRif you are allergic to omalizumab or any of the other ingredients of XOLAIR.


    How is XOLAIR given?

    XOLAIR is given as a subcutaneous injection.



    How often is XOLAIR* given?

    XOLAIR is given once every 2 or 4 weeks, depending on your dose. Your dose will be determined specifically for you, based on your body weight and your IgE level.


    How quickly does XOLAIR work?

    It is important to understand that XOLAIR may take time to work. So if you don’t feel a difference right away, it doesn’t mean that XOLAIR is not working.

    You should not reduce the dose of other asthma medications without first discussing it with your doctor, even if you are feeling better.


    Can you take XOLAIR with your current medications?

    XOLAIR can be used together with other medications for asthma, but it is still important to tell your doctor that you are taking them before you are given XOLAIR.


    What should you do if you have an asthma attack?

    If you have a sudden asthma attack, take your rescue medication as prescribed by your doctor and seek medical attention right away. XOLAIR is not a rescue medication and is not used to treat sudden asthma attacks.

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